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Review rating Excellent 4.8 | 847 Reviews
PeptiGlow™ Infusion System

Smooth deep crow's feet, lift sagging jowls, and erase stubborn lines and wrinkles in just a few, at-home treatments.

Product list description Smooths crow's feet and laugh lines naturally
Product list description Firms loose skin around jawline and neck
Product list description See visible improvement after just 1 treatment
Product list description Recommended by dermatologists nationwide
3 Months

3 Month Supply

6 Precision Infusion Treatments

$26.50/application

$49.50/application

You Save 46%

2 Months

2 Month Supply

4 Precision Infusion Treatments

$29.75/application

$49.50/application

You Save 39%

1 Month

1 Month Supply

2 Precision Infusion Treatments

$49.50/application

30 Day Satisfaction Guarantee
In Stock | Order Today, Ships by
Refund details Try it risk-free for 30 days. Love it or we’ll make it right.
Free Shipping to United States
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How PeptiGlow™ Infusion System Works

Why does this achieve results where premium skincare falls short?

Even the most sophisticated topical formulations cannot penetrate beyond the skin's protective barrier to reach the cellular layers where renewal actually occurs.

Our PeptiGlow™ System uses ultra-fine 24K gold-plated stainless steel micro-needles to create microscopic pathways directly into your skin's deeper layers.

This delivers powerful collagen-rebuilding peptides and plumping hyaluronic acid precisely where your skin needs it most – in the dermis where wrinkles form and sagging begins.

The result? Your skin finally gets the deep collagen support it's been missing, helping restore the firmness and radiance that naturally changes as we age.

Use every 2 weeks and watch your skin rebuild itself from the inside out.

1 PREP: Twist open the device and fill it with serum. Close it tightly after.
2 ACTIVATE: Turn upside down for 2 minutes so needles absorb serum completely.
3 TREAT: Gently stamp onto clean skin with (face, neck, lips) with slight overlap. Repeat 2-3 times per area.
4 ABSORB: Apply remaining serum and let absorb overnight. Proceed with your regular skincare routine as desired.
Is it comfortable and safe to use?

Will this hurt or damage my mature skin?

The micro-needles are thinner than a human hair (0.05mm), so it’s virtually 100% painless. If anything, you'll only feel a gentle tingling sensation – most women say it's actually quite pleasant and relaxing.

Our system is specifically designed for mature skin. It's dermatologist-approved, uses medical-grade sterile needle heads, and contains only the gentlest, most effective ingredients.

  • Designed for mature skin
  • Medical-grade sterile
  • Dermatologist approved
  • No harsh chemicals
Where can I use PeptiGlow™ for maximum anti-aging results?

It works practically everywhere because aging skin on the entire body is caused by the natural changes in collagen production over time.

Perform a treatment every 2 weeks to support your skin's natural renewal process

Use every 2 weeks on all areas for best results.

What's included in my order?

Everything you need for professional results at home

Each PeptiGlow™ package is designed for bi-weekly treatments. Every needle head is sterile and single-use for your safety.

Your complete system includes:

  • 1-Month Supply: 1 PeptiGlow Infusion Device with 24K gold-plated stainless steel micro-needles + 1 Additional 24K gold-plated stainless steel sterile needle head + 2 PeptiGlow™ Serums = 2 treatments
  • 2-Month Supply: 2 PeptiGlow Infusion Device with 24K gold-plated stainless steel micro-needles + 2 Additional 24K gold-plated stainless steel sterile needle heads + 4 PeptiGlow™ Serums = 4 treatments
  • 3-Month Supply: 3 PeptiGlow Infusion Device with 24K gold-plated stainless steel micro-needles + 3 Additional 24K gold-plated stainless steel sterile needle heads + 6 PeptiGlow™ Serums = 6 treatments

Each needle head and serum is intended for a single treatment session every 2 weeks and should not be reused.

30-Day Satisfaction Guarantee

With our clinically tested & proven system, we're confident in what we deliver. If you're not satisfied with the results for any reason, contact us and we’ll make it right.

Shipping & Returns

Shipping & Delivery

  • For orders outside the United States, please visit our international shipping page for applicable shipping rates.

Return Policy

  • if you're not completely satisfied, simply contact our 24/7 customer service team and we'll make it right.
Customer review
Michelle W.

"The lines around my eyes and lower face have definitely softened. My skin appeared fresher and glowing 🥰"

Excellent

PeptiGlow™ Transformations

Forehead Wrinkles & Frown Lines

Fine Lines & Expression Lines

Margaret H.

Softens forehead lines & expression marks naturally!

Visible results after just a few treatments!

Professional-quality results at home

I've been concerned about my forehead lines for years and considered expensive treatments, but I was hesitant. I tried PeptiGlow and couldn't be happier with how natural and refreshed I look.

Forehead Wrinkles & Frown Lines

Crow's Feet Enhancement

Alexandra L.

Say goodbye to crow's feet and restore natural firmness!

Visible results after just one month!

100% comfortable & safe

It's incredible - I never thought my crow's feet could look this much softer so quickly. My eyes look so much more refreshed.

Forehead Wrinkles & Frown Lines

Skin Tone & Radiance

Betty N.

Enhances natural radiance in just a few treatments

#1 recommendation by leading skincare experts

Results are guaranteed!

I thought expensive treatments were my only option for better skin tone, but fortunately PeptiGlow proved me wrong! My skin has this healthy glow again.

Forehead Wrinkles & Frown Lines

Lip Area Enhancement

Patricia R.

Instantly plumps and smooths lip area

Get natural looking fuller lips

Softens lip lines in just 1 treatment

This actually gave me natural fullness back to my lips, and looks completely natural - not like an artificial enhancement.

Forehead Wrinkles & Frown Lines

Overall Skin Improvement

Rebecca S.

Reduces fine lines & enhances firmness on face, lips & neck

Maximizes hydration for smooth, healthy-looking skin

Supports the skin's natural renewal for enhanced firmness

After just six treatments, I feel like I'm back to how my skin looked years ago! My skin has a beautiful glow, and it feels smoother and firmer than it has in ages.

Forehead Wrinkles & Frown Lines

Neck & Décolletage Renewal

Catherine M.

Smooths horizontal neck lines and enhances firmness

Restores natural skin texture in delicate areas

Professional results from home treatments

I was so self-conscious about my neck area, especially in business attire. The improvement has been remarkable - I feel confident wearing v-necks again.

How PeptiGlow™ Transforms Your Skin From The Inside Out

Precision Infusion Delivers Results Where Expensive Creams Fail

Those tiny, comfortable micro-needles create microscopic channels that penetrate far beyond your skin's surface, increasing active ingredient absorption by 300% and delivering clinically-proven age-reversing compounds exactly where aging occurs: deep in the collagen-producing layers.

While your expensive creams sit on top, PeptiGlow™ ensures every drop of collagen-boosting serum reaches the cellular level where real transformation happens.

Experienced dramatically smoother skin with fewer visible lines
Found treatments completely painless
Achieved noticeably firmer, more lifted skin on face and neck
Said friends and family noticed they looked younger

Get Youthful Skin in 4 Easy Steps

Dermatologists recommend one treatment every 2 weeks for optimal results.

Twist open the system

Leave the bottle upside down for 2 minutes, so the touchpoints can soak up the serum.

Gently press the tool onto your skin (face, lips, neck etc.) with a 50% overlap. Repeat for 2-3 passes for best results.

Apply any excess serum to your face and let the serum absorb into your skin overnight, and optionally, you can apply your regular skincare

Powerful Ingredients That Bring Results

Hydrolyzed Collagen

Rebuilds your skin's structural foundation from within. Clinical studies show significant improvement in skin thickness and wrinkle reduction after just 4 weeks of use.

Acetyl Hexapeptide-8

Advanced peptide that helps relax facial muscles to smooth expression lines. Clinically proven to reduce wrinkle depth by up to 30% through gentle, natural processes.

Dual-Form Hyaluronic Acid (Hydrolyzed + Sodium Hyaluronate)

Two molecular sizes penetrate different skin depths for comprehensive hydration. Holds 1,000 times its weight in water to plump skin and fill lines from within.

Egothioneine (The Longevity Molecule)

Nature's most powerful antioxidant that protects cellular vitality and supports your skin's natural resilience. Found in the cells of the world's longest-living organisms.

View All Ingredients
Water, Filtrate of Fermentation Products of Bifidobacteria, Glycerin, Hydrolyzed Collagen, Acetyl Hexapeptide - 8, Hydrolyzed Hyaluronic Acid, Palmitoryl Tetrapeptide - 7, Acetyl Tetrapeptide - 11, Citrus Aurantium Amara(Bitter Orange)Flower Water, Sodium Chloride, Palmitoyl Oligopeptide,Mannitol, Ergothioneine, Acetyl Tetrapeptide - 9, Palmitoryl Tripeptide - 1, 1,2 - Hexanediol, Sodium Hyaluronate, P - Hydroxyphenylethanone, Arginine, Arginine/Lysine Polypeptides, Sodium Lactate, Disodium Ethylenediaminetetracetic Acid, Citric Acid

Making an Informed Choice for Your Skin

Created by Scientists, Recommended by Dermatologists

"PeptiGlow represents a significant advancement in evidence-based skincare technology. The precision delivery system achieves cellular-level results that align with clinical-grade outcomes."

"I recommend PeptiGlow to patients seeking scientifically-validated results without clinical procedures. The peptide absorption technology is genuinely impressive from a research perspective."

"Finally, a system that addresses mature skin through evidence-based biotechnology rather than marketing claims. The clinical outcomes support the scientific foundation."

Your Satisfaction is Our Promise

Try PeptiGlow™ Infusion System with complete peace of mind at no risk. Backed by research and a complete 30-day satisfaction guarantee, reflecting our commitment to proven results.

From our experience supporting women's skin health, we know PeptiGlow™ delivers the enhanced firmness and natural radiance you're looking for. Love it or we'll make it right.

Our professional care team at support@evolenne.com is here to ensure you have the best possible experience with your skin.

Frequently Asked Questions

How many treatments are in each kit and how often should I use it?

Usage: Every 2 weeks

Note: Each needle head is sterile and single-use only.

1-Month Supply

  • 1 PeptiGlow Infusion Device with 24K gold-plated stainless steel micro-needles
  • 1 Additional 24K gold-plated stainless steel sterile needle head
  • 2 PeptiGlow™ Serums

Treatments: 2

2-Month Supply

  • 2 PeptiGlow Infusion Devices with 24K gold-plated stainless steel micro-needles
  • 2 Additional 24K gold-plated stainless steel sterile needle heads
  • 4 PeptiGlow™ Serums

Treatments: 4

3-Month Supply

  • 3 PeptiGlow Infusion Devices with 24K gold-plated stainless steel micro-needles
  • 3 Additional 24K gold-plated stainless steel sterile needle heads
  • 6 PeptiGlow™ Serums

Treatments: 6

Can I reuse the needle heads?
No, each needle head must be thrown away after one use to prevent infection and maintain effectiveness. This is a medical-grade device with medical-grade safety standards.
How does the micro-needling actually work?
The ultra-fine needles create tiny, temporary channels in your skin's surface. This allows the collagen peptides and hyaluronic acid to penetrate deep into the layers where aging happens, rather than just sitting on top like regular creams.
How fast will I see results?
Right after your first treatment, your skin will feel smoother and look more hydrated. Most women see visible improvement in fine lines after 2-3 treatments (4-6 weeks). For deeper wrinkles and sagging, expect significant improvement after 6 treatments (12 weeks).
Does it hurt?
No! The needles are 0.05mm thick (thinner than hair) so you'll only feel gentle tingling. 94% of users rate it as completely comfortable. Much more comfortable than professional microneedling.
Is this safe for mature/sensitive skin?
Absolutely. The system was specifically designed for women over 50 with mature, often sensitive skin. All ingredients are dermatologist-tested and the needle depth is perfectly calibrated for safety and comfort.
Can I use this around my eyes and on my lips?
Yes! It's perfect for crow's feet (stay 3mm away from the actual eye), lip lines, and even directly on lips for natural plumping. Many users say their lip lines disappear completely.
What if I have active acne or rosacea?
It is not recommended for individuals with serious skin conditions like rosacea, eczema, or aggressive acne, as these conditions may be aggravated. However, this system can actually help with acne scars and post-inflammatory marks once the active inflammation subsides. If you have specific concerns or medical conditions, consult with a dermatologist before use.
How is this different from dermarolling?
Completely different. Dermarollers drag needles across skin causing micro-tears. PeptiGlow STAMPS straight down with precision micro-needles, creating clean channels without damage. Plus, ours delivers medical-grade peptides directly into these channels.
Can I use my own serums with this?
We don't recommend it. Our serum is specifically formulated with the right molecular weights and concentrations to work with the micro-channels. Other products may be too harsh or ineffective.
What are the ingredients?
Water, Filtrate of Fermentation Products of Bifidobacteria, Glycerin, Hydrolyzed Collagen, Acetyl Hexapeptide - 8, Hydrolyzed Hyaluronic Acid, Palmitoryl Tetrapeptide - 7, Acetyl Tetrapeptide - 11, Citrus Aurantium Amara(Bitter Orange)Flower Water, Sodium Chloride, Palmitoyl Oligopeptide,Mannitol, Ergothioneine, Acetyl Tetrapeptide - 9, Palmitoryl Tripeptide - 1, 1,2 - Hexanediol, Sodium Hyaluronate, P - Hydroxyphenylethanone, Arginine, Arginine/Lysine Polypeptides, Sodium Lactate, Disodium Ethylenediaminetetracetic Acid, Citric Acid
What if I'm on retinoids or other active ingredients?
Stop retinoids 48 hours before treatment and wait 48 hours after to restart. You can use gentle moisturizers and sunscreen immediately after treatment.
How long do results last?
Results improve cumulatively with each treatment. Most women maintain results with one treatment every 3-4 weeks after their initial 3-month series. Some continue bi-weekly for maximum benefits.
What's your return policy?
30-day complete satisfaction guarantee. If you're not thrilled with your results for any reason, contact support@evolenne.com and we’ll make it right.
Does this work on neck and chest wrinkles?
Yes! Neck lines, chest wrinkles, and décolletage aging respond excellently. Many users say their neck looks years younger after consistent treatments.
How does this compare to Botox or fillers?
This works differently – instead of paralyzing muscles (Botox) or adding volume (fillers), it helps your skin rebuild its own collagen naturally. Results develop gradually and look completely natural. No risk of looking 'frozen' or 'overdone.'
What if I miss treatments or stop for a while?
Your skin won't lose its improvements, but new aging will continue. You can restart anytime – even after months off. Your skin will respond just as well as before.
Is there any downtime?
Minimal. You may have slight pinkness for 2-6 hours (like a mild sunburn). Avoid makeup and sun for 12 hours. Many women do treatments Friday night and look perfect by Monday.
How much skin does one treatment cover?
One serum vial easily covers your entire face, neck, and any problem areas with extra left over. The coverage is very generous – you'll never run out mid-treatment.

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30 Days Satisfaction Guarantee

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Customer Reviews

Based on 202 reviews
50%
(100)
41%
(82)
7%
(15)
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2%
(5)
L
Linda B.
Solid investment

Takes time but worth it. My forehead looks smoother and skin feels tighter.

J
Joyce L.
Good experience

My skin feels firmer and looks more radiant. The needles are surprisingly comfortable.

J
Joyce K.
EXCELLENT

Worth every cent!

J
Jennifer R.
Life changing results

This has restored my confidence. The sagging around my neck has improved and my face looks so much more lifted.

K
Kelly S.
Amazing

This product is incredible!